Abstract: Norman E. Borlaug, Nobel Prize Laureate for peace in 1970, suggested “Blue Revolution-more crop for every drop” in 1999. According to the situation of water resources and the strategy for regulating water stress in China, five stratagems of research and management for carrying out“Blue Revolution” were suggested such as exploring rainfall from atmosphere, conservation and regulation of rainfall, macroscopic regulation of water resources from different regions, water saving agriculture, biological water saving. The guick advances in study genetics and breeding of crop drought resistance and water use efficiency, especially in gene locating and transgenic crop are notable. Our new research advance in water use efficiency in wheat is also introduced. Finally, it is pointed out that agriculture in the 21st century will be of high technology and high efficiency,combining with traditional breeding and transgenic technology. More new good crop varieties will be brought out in future, that are characterized by good pest and disease resistance, unfavorable stress resistance, and efficient use of nutrition, water, solar energy.